Troubleshooting Dissolution Methods for Solid Oral Dosage Forms


Instructor: Mark Powell
Product ID: 706599

  • Duration: 60 Min
The root cause of variable or inconsistent data from compendial dissolution tests can be difficult to identify. Formulation, equipment, operator error and incorrect calculation may be factors. This webinar presents a systematic, logical approach to investigating anomalous dissolution results.
Last Recorded Date: Oct-2021


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Why Should You Attend:

Pharmaceutical dissolution testing for solid oral dosage forms is a complex analytical procedure where the control of critical variables (environmental conditions, equipment performance, sample introduction, sampling and dissolution medium preparation) is important for achieving consistent results. With so many factors at play, assigning root cause to anomalous data can be difficult.

By attending this webinar, you will learn how to approach dissolution OOS/OOT investigations in a systematic, rigorous manner.

The benefits of attending this webinar include:

  • A logical roadmap for investigating anomalous dissolution data
  • Improved understanding of the critical factors affecting dissolution test variability
  • Operator-controlled factors such as sample handling, sample introduction, sampling/filtration and results calculation that can affect result reliability Common errors in dissolution testing

Areas Covered in the Webinar:

  • Equipment set-up errors
  • Sample introduction
  • Observations
  • Sampling and filtration
  • Causes of excessive variability
  • Outliers
  • Method documentation
  • Correct calculations (with/without media replacement)

Who Will Benefit:

  • Development/QC analysts
  • Laboratory managers
  • QA professionals
  • Formulation/production scientists
Instructor Profile:
Mark Powell

Mark Powell
Director, Mark Powell Scientific Limited

Dr Mark Powell is a Fellow of the Royal Society of Chemistry (RSC) with over thirty years’ experience as an analytical chemist. Mark was Honorary Treasurer of the RSC’s Analytical Division and led a working group on continuing professional development until July 2016, when his term of office ended. Between 2003 and 2013, he was the Analytical Development Manager, and later Scientific Manager, of a UK-based contract research organization which specialized in early-stage oral drug development. In 2013, he set up Mark Powell Scientific Limited, which provides training and consultancy services to pharmaceutical companies. Mark has since enjoyed working with companies of all sizes around the world on a variety of training and consultancy assignments.

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Our refund policy is governed by individual products and services refund policy mentioned against each of offerings. However in absence of specific refund policy of an offering below refund policy will be effective.
Registrants may cancel up to two working days prior to the course start date and will receive a letter of credit to be used towards a future course up to one year from date of issuance. ComplianceOnline would process/provide refund if the Live Webinar has been cancelled. The attendee could choose between the recorded version of the webinar or refund for any cancelled webinar. Refunds will not be given to participants who do not show up for the webinar. On-Demand Recordings can be requested in exchange. Webinar may be cancelled due to lack of enrolment or unavoidable factors. Registrants will be notified 24hours in advance if a cancellation occurs. Substitutions can happen any time. On-Demand Recording purchases will not be refunded as it is available for immediate streaming. However if you are not able to view the webinar or you have any concern about the content of the webinar please contact us at below email or by call mentioning your feedback for resolution of the matter. We respect feedback/opinions of our customers which enables us to improve our products and services. To contact us please email [email protected] call +1-888-717-2436 (Toll Free).




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