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Home ›  Best Practices

ICH Q7 - GOOD MANUFACTURING PRACTICE GUIDE FOR ACTIVE PHARMACEUTICAL INGREDIENTS

  • Date: January 11, 2011
  • Source: http://private.ich.org/
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This document (Guide) is intended to provide guidance regarding good manufacturing practice (GMP) for the manufacturing of active pharmaceutical ingredients (APIs) under an appropriate system for managing quality. It is also intended to help ensure that APIs meet the requirements for quality and purity that they purport or are represented to possess.

This Guide applies to the manufacture of APIs for use in human drug (medicinal) products. It applies to the manufacture of sterile APIs only up to the point immediately prior to the APIs being rendered sterile. The sterilization and aseptic processing of sterile APIs are not covered by this guidance, but should be performed in accordance with GMP guidelines for drug (medicinal) products as defined by local authorities.

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Method public java.lang.String org.ofbiz.widget.screen.ScreenRenderer.render(java.lang.String) throws org.ofbiz.base.util.GeneralException,java.io.IOException,org.xml.sax.SAXException,javax.xml.parsers.ParserConfigurationException threw an exception when invoked on org.ofbiz.widget.screen.ScreenRenderer@235c880d with arguments of types [java.lang.String,] The problematic instruction: ---------- ==> ${screens.render("component://ecommerce/widget/CONew2016/BestPracticesPageScreens.xml#trainings-article-detail")} [on line 9, column 17 in component://ecommerce/webapp/ecommerce/CONew2016/bestpractices/article_detail/contentDetailMain.ftl] ---------- Java backtrace for programmers: ---------- freemarker.template.TemplateModelException: Method public java.lang.String org.ofbiz.widget.screen.ScreenRenderer.render(java.lang.String) throws org.ofbiz.base.util.GeneralException,java.io.IOException,org.xml.sax.SAXException,javax.xml.parsers.ParserConfigurationException threw an exception when invoked on org.ofbiz.widget.screen.ScreenRenderer@235c880d with arguments of types [java.lang.String,] at freemarker.ext.beans.OverloadedMethodModel.exec(OverloadedMethodModel.java:134) at freemarker.core.MethodCall._getAsTemplateModel(MethodCall.java:93) at freemarker.core.Expression.getAsTemplateModel(Expression.java:89) at freemarker.core.Expression.getStringValue(Expression.java:93) at freemarker.core.DollarVariable.accept(DollarVariable.java:76) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.MixedContent.accept(MixedContent.java:92) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.Environment.process(Environment.java:199) at org.ofbiz.base.util.template.FreeMarkerWorker.renderTemplate(FreeMarkerWorker.java:257) at org.ofbiz.widget.screen.HtmlWidget.renderHtmlTemplate(HtmlWidget.java:225) at org.ofbiz.widget.screen.HtmlWidget$HtmlTemplate.renderWidgetString(HtmlWidget.java:270) at org.ofbiz.widget.screen.HtmlWidget.renderWidgetString(HtmlWidget.java:130) at org.ofbiz.widget.screen.ModelScreenWidget$PlatformSpecific.renderWidgetString(ModelScreenWidget.java:920) at org.ofbiz.widget.screen.ModelScreenWidget.renderSubWidgetsString(ModelScreenWidget.java:104) at org.ofbiz.widget.screen.ModelScreenWidget$Section.renderWidgetString(ModelScreenWidget.java:191) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:396) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:135) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:97) at sun.reflect.GeneratedMethodAccessor64.invoke(Unknown Source) at sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43) at java.lang.reflect.Method.invoke(Method.java:498) at freemarker.ext.beans.BeansWrapper.invokeMethod(BeansWrapper.java:866) at freemarker.ext.beans.OverloadedMethodModel.exec(OverloadedMethodModel.java:104) at freemarker.core.MethodCall._getAsTemplateModel(MethodCall.java:93) at freemarker.core.Expression.getAsTemplateModel(Expression.java:89) at freemarker.core.Expression.getStringValue(Expression.java:93) at freemarker.core.DollarVariable.accept(DollarVariable.java:76) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.MixedContent.accept(MixedContent.java:92) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.Environment.process(Environment.java:199) at org.ofbiz.base.util.template.FreeMarkerWorker.renderTemplate(FreeMarkerWorker.java:257) at org.ofbiz.widget.screen.HtmlWidget.renderHtmlTemplate(HtmlWidget.java:225) at org.ofbiz.widget.screen.HtmlWidget$HtmlTemplate.renderWidgetString(HtmlWidget.java:270) at org.ofbiz.widget.screen.HtmlWidget.renderWidgetString(HtmlWidget.java:130) at org.ofbiz.widget.screen.ModelScreenWidget$PlatformSpecific.renderWidgetString(ModelScreenWidget.java:920) at org.ofbiz.widget.screen.ModelScreenWidget.renderSubWidgetsString(ModelScreenWidget.java:104) at org.ofbiz.widget.screen.ModelScreenWidget$Section.renderWidgetString(ModelScreenWidget.java:191) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:396) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:135) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:97) at org.ofbiz.widget.screen.MacroScreenViewHandler.render(MacroScreenViewHandler.java:104) at org.ofbiz.webapp.control.RequestHandler.renderView(RequestHandler.java:865) at org.ofbiz.webapp.control.RequestHandler.doRequest(RequestHandler.java:582) at org.ofbiz.webapp.control.RequestHandler.doRequest(RequestHandler.java:547) at org.ofbiz.webapp.control.RequestHandler.doRequest(RequestHandler.java:547) at org.ofbiz.webapp.control.ControlServlet.doGet(ControlServlet.java:224) at javax.servlet.http.HttpServlet.service(HttpServlet.java:621) at javax.servlet.http.HttpServlet.service(HttpServlet.java:722) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:305) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:210) at org.apache.catalina.core.ApplicationDispatcher.invoke(ApplicationDispatcher.java:749) at org.apache.catalina.core.ApplicationDispatcher.processRequest(ApplicationDispatcher.java:487) at org.apache.catalina.core.ApplicationDispatcher.doForward(ApplicationDispatcher.java:412) at org.apache.catalina.core.ApplicationDispatcher.forward(ApplicationDispatcher.java:339) at com.metricstream.SEOServlet.dispatchEcommerceRequest(SEOServlet.java:287) at com.metricstream.SEOServlet.findPattern(SEOServlet.java:236) at com.metricstream.SEOServlet.doGet(SEOServlet.java:49) at javax.servlet.http.HttpServlet.service(HttpServlet.java:621) at javax.servlet.http.HttpServlet.service(HttpServlet.java:722) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:305) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:210) at org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:222) at org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:123) at org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:472) at org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:168) at org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:99) at org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:118) at org.apache.catalina.valves.AccessLogValve.invoke(AccessLogValve.java:929) at org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:407) at org.apache.coyote.http11.AbstractHttp11Processor.process(AbstractHttp11Processor.java:1002) at org.apache.coyote.AbstractProtocol$AbstractConnectionHandler.process(AbstractProtocol.java:585) at org.apache.tomcat.util.net.JIoEndpoint$SocketProcessor.run(JIoEndpoint.java:310) at java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1149) at java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:624) at java.lang.Thread.run(Thread.java:748) Caused by: org.ofbiz.widget.screen.ScreenRenderException: Error rendering screen [component://ecommerce/widget/CONew2016/BestPracticesPageScreens.xml#trainings-article-detail]: java.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object (Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:409) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:135) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:97) at sun.reflect.GeneratedMethodAccessor64.invoke(Unknown Source) at sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43) at java.lang.reflect.Method.invoke(Method.java:498) at freemarker.ext.beans.BeansWrapper.invokeMethod(BeansWrapper.java:866) at freemarker.ext.beans.OverloadedMethodModel.exec(OverloadedMethodModel.java:104) ... 76 more Caused by: java.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object at org.ofbiz.base.util.ScriptUtil.executeScript(ScriptUtil.java:348) at org.ofbiz.base.util.ScriptUtil.executeScript(ScriptUtil.java:324) at org.ofbiz.widget.ModelWidgetAction$Script.runAction(ModelWidgetAction.java:416) at org.ofbiz.widget.ModelWidgetAction.runSubActions(ModelWidgetAction.java:116) at org.ofbiz.widget.screen.ModelScreenWidget$Section.renderWidgetString(ModelScreenWidget.java:184) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:396) ... 83 more
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Method public java.lang.String org.ofbiz.widget.screen.ScreenRenderer.render(java.lang.String) throws org.ofbiz.base.util.GeneralException,java.io.IOException,org.xml.sax.SAXException,javax.xml.parsers.ParserConfigurationException threw an exception when invoked on org.ofbiz.widget.screen.ScreenRenderer@235c880d with arguments of types [java.lang.String,] The problematic instruction: ---------- ==> ${screens.render("component://ecommerce/widget/CONew2016/BaseScreens.xml#recently-viewed")} [on line 28, column 1 in component://ecommerce/webapp/ecommerce/CONew2016/bestpractices/article_detail/contentDetailMain.ftl] ---------- Java backtrace for programmers: ---------- freemarker.template.TemplateModelException: Method public java.lang.String org.ofbiz.widget.screen.ScreenRenderer.render(java.lang.String) throws org.ofbiz.base.util.GeneralException,java.io.IOException,org.xml.sax.SAXException,javax.xml.parsers.ParserConfigurationException threw an exception when invoked on org.ofbiz.widget.screen.ScreenRenderer@235c880d with arguments of types [java.lang.String,] at freemarker.ext.beans.OverloadedMethodModel.exec(OverloadedMethodModel.java:134) at freemarker.core.MethodCall._getAsTemplateModel(MethodCall.java:93) at freemarker.core.Expression.getAsTemplateModel(Expression.java:89) at freemarker.core.Expression.getStringValue(Expression.java:93) at freemarker.core.DollarVariable.accept(DollarVariable.java:76) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.MixedContent.accept(MixedContent.java:92) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.Environment.process(Environment.java:199) at org.ofbiz.base.util.template.FreeMarkerWorker.renderTemplate(FreeMarkerWorker.java:257) at org.ofbiz.widget.screen.HtmlWidget.renderHtmlTemplate(HtmlWidget.java:225) at org.ofbiz.widget.screen.HtmlWidget$HtmlTemplate.renderWidgetString(HtmlWidget.java:270) at org.ofbiz.widget.screen.HtmlWidget.renderWidgetString(HtmlWidget.java:130) at org.ofbiz.widget.screen.ModelScreenWidget$PlatformSpecific.renderWidgetString(ModelScreenWidget.java:920) at org.ofbiz.widget.screen.ModelScreenWidget.renderSubWidgetsString(ModelScreenWidget.java:104) at org.ofbiz.widget.screen.ModelScreenWidget$Section.renderWidgetString(ModelScreenWidget.java:191) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:396) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:135) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:97) at sun.reflect.GeneratedMethodAccessor64.invoke(Unknown Source) at sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43) at java.lang.reflect.Method.invoke(Method.java:498) at freemarker.ext.beans.BeansWrapper.invokeMethod(BeansWrapper.java:866) at freemarker.ext.beans.OverloadedMethodModel.exec(OverloadedMethodModel.java:104) at freemarker.core.MethodCall._getAsTemplateModel(MethodCall.java:93) at freemarker.core.Expression.getAsTemplateModel(Expression.java:89) at freemarker.core.Expression.getStringValue(Expression.java:93) at freemarker.core.DollarVariable.accept(DollarVariable.java:76) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.MixedContent.accept(MixedContent.java:92) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.Environment.process(Environment.java:199) at org.ofbiz.base.util.template.FreeMarkerWorker.renderTemplate(FreeMarkerWorker.java:257) at org.ofbiz.widget.screen.HtmlWidget.renderHtmlTemplate(HtmlWidget.java:225) at org.ofbiz.widget.screen.HtmlWidget$HtmlTemplate.renderWidgetString(HtmlWidget.java:270) at org.ofbiz.widget.screen.HtmlWidget.renderWidgetString(HtmlWidget.java:130) at org.ofbiz.widget.screen.ModelScreenWidget$PlatformSpecific.renderWidgetString(ModelScreenWidget.java:920) at org.ofbiz.widget.screen.ModelScreenWidget.renderSubWidgetsString(ModelScreenWidget.java:104) at org.ofbiz.widget.screen.ModelScreenWidget$Section.renderWidgetString(ModelScreenWidget.java:191) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:396) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:135) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:97) at org.ofbiz.widget.screen.MacroScreenViewHandler.render(MacroScreenViewHandler.java:104) at org.ofbiz.webapp.control.RequestHandler.renderView(RequestHandler.java:865) at org.ofbiz.webapp.control.RequestHandler.doRequest(RequestHandler.java:582) at org.ofbiz.webapp.control.RequestHandler.doRequest(RequestHandler.java:547) at org.ofbiz.webapp.control.RequestHandler.doRequest(RequestHandler.java:547) at org.ofbiz.webapp.control.ControlServlet.doGet(ControlServlet.java:224) at javax.servlet.http.HttpServlet.service(HttpServlet.java:621) at javax.servlet.http.HttpServlet.service(HttpServlet.java:722) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:305) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:210) at org.apache.catalina.core.ApplicationDispatcher.invoke(ApplicationDispatcher.java:749) at org.apache.catalina.core.ApplicationDispatcher.processRequest(ApplicationDispatcher.java:487) at org.apache.catalina.core.ApplicationDispatcher.doForward(ApplicationDispatcher.java:412) at org.apache.catalina.core.ApplicationDispatcher.forward(ApplicationDispatcher.java:339) at com.metricstream.SEOServlet.dispatchEcommerceRequest(SEOServlet.java:287) at com.metricstream.SEOServlet.findPattern(SEOServlet.java:236) at com.metricstream.SEOServlet.doGet(SEOServlet.java:49) at javax.servlet.http.HttpServlet.service(HttpServlet.java:621) at javax.servlet.http.HttpServlet.service(HttpServlet.java:722) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:305) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:210) at org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:222) at org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:123) at org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:472) at org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:168) at org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:99) at org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:118) at org.apache.catalina.valves.AccessLogValve.invoke(AccessLogValve.java:929) at org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:407) at org.apache.coyote.http11.AbstractHttp11Processor.process(AbstractHttp11Processor.java:1002) at org.apache.coyote.AbstractProtocol$AbstractConnectionHandler.process(AbstractProtocol.java:585) at org.apache.tomcat.util.net.JIoEndpoint$SocketProcessor.run(JIoEndpoint.java:310) at java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1149) at java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:624) at java.lang.Thread.run(Thread.java:748) Caused by: org.ofbiz.widget.screen.ScreenRenderException: Error rendering screen [component://ecommerce/widget/CONew2016/BaseScreens.xml#recently-viewed]: org.ofbiz.entity.transaction.GenericTransactionException: The current transaction is marked for rollback, not beginning a new transaction and aborting current operation; the rollbackOnly was caused by: Error rendering screen [component://ecommerce/widget/CONew2016/BestPracticesPageScreens.xml#trainings-article-detail]: java.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null objectjava.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object (Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object) (The current transaction is marked for rollback, not beginning a new transaction and aborting current operation; the rollbackOnly was caused by: Error rendering screen [component://ecommerce/widget/CONew2016/BestPracticesPageScreens.xml#trainings-article-detail]: java.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null objectjava.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object (Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object)) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:423) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:135) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:97) at sun.reflect.GeneratedMethodAccessor64.invoke(Unknown Source) at sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43) at java.lang.reflect.Method.invoke(Method.java:498) at freemarker.ext.beans.BeansWrapper.invokeMethod(BeansWrapper.java:866) at freemarker.ext.beans.OverloadedMethodModel.exec(OverloadedMethodModel.java:104) ... 76 more Caused by: org.ofbiz.entity.transaction.GenericTransactionException: The current transaction is marked for rollback, not beginning a new transaction and aborting current operation; the rollbackOnly was caused by: Error rendering screen [component://ecommerce/widget/CONew2016/BestPracticesPageScreens.xml#trainings-article-detail]: java.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null objectjava.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object (Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object) at org.ofbiz.entity.transaction.TransactionUtil.begin(TransactionUtil.java:159) at org.ofbiz.entity.transaction.TransactionUtil.begin(TransactionUtil.java:127) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:388) ... 83 more Caused by: java.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object at org.ofbiz.base.util.ScriptUtil.executeScript(ScriptUtil.java:348) at org.ofbiz.base.util.ScriptUtil.executeScript(ScriptUtil.java:324) at org.ofbiz.widget.ModelWidgetAction$Script.runAction(ModelWidgetAction.java:416) at org.ofbiz.widget.ModelWidgetAction.runSubActions(ModelWidgetAction.java:116) at org.ofbiz.widget.screen.ModelScreenWidget$Section.renderWidgetString(ModelScreenWidget.java:184) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:396) ... 83 more
Method public java.lang.String org.ofbiz.widget.screen.ScreenRenderer.render(java.lang.String) throws org.ofbiz.base.util.GeneralException,java.io.IOException,org.xml.sax.SAXException,javax.xml.parsers.ParserConfigurationException threw an exception when invoked on org.ofbiz.widget.screen.ScreenRenderer@235c880d with arguments of types [java.lang.String,] The problematic instruction: ---------- ==> ${screens.render("component://ecommerce/widget/CONew2016/BaseScreens.xml#main-footer")} [on line 11, column 1 in component://ecommerce/webapp/ecommerce/CONew2016/templates/articleDetail.ftl] ---------- Java backtrace for programmers: ---------- freemarker.template.TemplateModelException: Method public java.lang.String org.ofbiz.widget.screen.ScreenRenderer.render(java.lang.String) throws org.ofbiz.base.util.GeneralException,java.io.IOException,org.xml.sax.SAXException,javax.xml.parsers.ParserConfigurationException threw an exception when invoked on org.ofbiz.widget.screen.ScreenRenderer@235c880d with arguments of types [java.lang.String,] at freemarker.ext.beans.OverloadedMethodModel.exec(OverloadedMethodModel.java:134) at freemarker.core.MethodCall._getAsTemplateModel(MethodCall.java:93) at freemarker.core.Expression.getAsTemplateModel(Expression.java:89) at freemarker.core.Expression.getStringValue(Expression.java:93) at freemarker.core.DollarVariable.accept(DollarVariable.java:76) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.MixedContent.accept(MixedContent.java:92) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.Environment.process(Environment.java:199) at org.ofbiz.base.util.template.FreeMarkerWorker.renderTemplate(FreeMarkerWorker.java:257) at org.ofbiz.widget.screen.HtmlWidget.renderHtmlTemplate(HtmlWidget.java:225) at org.ofbiz.widget.screen.HtmlWidget$HtmlTemplate.renderWidgetString(HtmlWidget.java:270) at org.ofbiz.widget.screen.HtmlWidget.renderWidgetString(HtmlWidget.java:130) at org.ofbiz.widget.screen.ModelScreenWidget$PlatformSpecific.renderWidgetString(ModelScreenWidget.java:920) at org.ofbiz.widget.screen.ModelScreenWidget.renderSubWidgetsString(ModelScreenWidget.java:104) at org.ofbiz.widget.screen.ModelScreenWidget$Section.renderWidgetString(ModelScreenWidget.java:191) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:396) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:135) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:97) at org.ofbiz.widget.screen.MacroScreenViewHandler.render(MacroScreenViewHandler.java:104) at org.ofbiz.webapp.control.RequestHandler.renderView(RequestHandler.java:865) at org.ofbiz.webapp.control.RequestHandler.doRequest(RequestHandler.java:582) at org.ofbiz.webapp.control.RequestHandler.doRequest(RequestHandler.java:547) at org.ofbiz.webapp.control.RequestHandler.doRequest(RequestHandler.java:547) at org.ofbiz.webapp.control.ControlServlet.doGet(ControlServlet.java:224) at javax.servlet.http.HttpServlet.service(HttpServlet.java:621) at javax.servlet.http.HttpServlet.service(HttpServlet.java:722) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:305) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:210) at org.apache.catalina.core.ApplicationDispatcher.invoke(ApplicationDispatcher.java:749) at org.apache.catalina.core.ApplicationDispatcher.processRequest(ApplicationDispatcher.java:487) at org.apache.catalina.core.ApplicationDispatcher.doForward(ApplicationDispatcher.java:412) at org.apache.catalina.core.ApplicationDispatcher.forward(ApplicationDispatcher.java:339) at com.metricstream.SEOServlet.dispatchEcommerceRequest(SEOServlet.java:287) at com.metricstream.SEOServlet.findPattern(SEOServlet.java:236) at com.metricstream.SEOServlet.doGet(SEOServlet.java:49) at javax.servlet.http.HttpServlet.service(HttpServlet.java:621) at javax.servlet.http.HttpServlet.service(HttpServlet.java:722) at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:305) at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:210) at org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:222) at org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:123) at org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:472) at org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:168) at org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:99) at org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:118) at org.apache.catalina.valves.AccessLogValve.invoke(AccessLogValve.java:929) at org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:407) at org.apache.coyote.http11.AbstractHttp11Processor.process(AbstractHttp11Processor.java:1002) at org.apache.coyote.AbstractProtocol$AbstractConnectionHandler.process(AbstractProtocol.java:585) at org.apache.tomcat.util.net.JIoEndpoint$SocketProcessor.run(JIoEndpoint.java:310) at java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1149) at java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:624) at java.lang.Thread.run(Thread.java:748) Caused by: org.ofbiz.widget.screen.ScreenRenderException: Error rendering screen [component://ecommerce/widget/CONew2016/BaseScreens.xml#main-footer]: org.ofbiz.entity.transaction.GenericTransactionException: The current transaction is marked for rollback, not beginning a new transaction and aborting current operation; the rollbackOnly was caused by: Error rendering screen [component://ecommerce/widget/CONew2016/BestPracticesPageScreens.xml#trainings-article-detail]: java.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null objectjava.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object (Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object) (The current transaction is marked for rollback, not beginning a new transaction and aborting current operation; the rollbackOnly was caused by: Error rendering screen [component://ecommerce/widget/CONew2016/BestPracticesPageScreens.xml#trainings-article-detail]: java.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null objectjava.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object (Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object)) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:423) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:135) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:97) at sun.reflect.GeneratedMethodAccessor64.invoke(Unknown Source) at sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43) at java.lang.reflect.Method.invoke(Method.java:498) at freemarker.ext.beans.BeansWrapper.invokeMethod(BeansWrapper.java:866) at freemarker.ext.beans.OverloadedMethodModel.exec(OverloadedMethodModel.java:104) ... 53 more Caused by: org.ofbiz.entity.transaction.GenericTransactionException: The current transaction is marked for rollback, not beginning a new transaction and aborting current operation; the rollbackOnly was caused by: Error rendering screen [component://ecommerce/widget/CONew2016/BestPracticesPageScreens.xml#trainings-article-detail]: java.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null objectjava.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object (Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object) at org.ofbiz.entity.transaction.TransactionUtil.begin(TransactionUtil.java:159) at org.ofbiz.entity.transaction.TransactionUtil.begin(TransactionUtil.java:127) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:388) ... 60 more Caused by: java.lang.IllegalArgumentException: Error running script at location [component://ecommerce/webapp/ecommerce/WEB-INF/actions/CONew2016/bestpractices/article_detail/trainings_articleDetail.groovy]: javax.script.ScriptException: java.lang.NullPointerException: Cannot invoke method getString() on null object at org.ofbiz.base.util.ScriptUtil.executeScript(ScriptUtil.java:348) at org.ofbiz.base.util.ScriptUtil.executeScript(ScriptUtil.java:324) at org.ofbiz.widget.ModelWidgetAction$Script.runAction(ModelWidgetAction.java:416) at org.ofbiz.widget.ModelWidgetAction.runSubActions(ModelWidgetAction.java:116) at org.ofbiz.widget.screen.ModelScreenWidget$Section.renderWidgetString(ModelScreenWidget.java:184) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:396) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:135) at org.ofbiz.widget.screen.ScreenRenderer.render(ScreenRenderer.java:97) at sun.reflect.GeneratedMethodAccessor64.invoke(Unknown Source) at sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43) at java.lang.reflect.Method.invoke(Method.java:498) at freemarker.ext.beans.BeansWrapper.invokeMethod(BeansWrapper.java:866) at freemarker.ext.beans.OverloadedMethodModel.exec(OverloadedMethodModel.java:104) at freemarker.core.MethodCall._getAsTemplateModel(MethodCall.java:93) at freemarker.core.Expression.getAsTemplateModel(Expression.java:89) at freemarker.core.Expression.getStringValue(Expression.java:93) at freemarker.core.DollarVariable.accept(DollarVariable.java:76) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.MixedContent.accept(MixedContent.java:92) at freemarker.core.Environment.visit(Environment.java:221) at freemarker.core.Environment.process(Environment.java:199) at org.ofbiz.base.util.template.FreeMarkerWorker.renderTemplate(FreeMarkerWorker.java:257) at org.ofbiz.widget.screen.HtmlWidget.renderHtmlTemplate(HtmlWidget.java:225) at org.ofbiz.widget.screen.HtmlWidget$HtmlTemplate.renderWidgetString(HtmlWidget.java:270) at org.ofbiz.widget.screen.HtmlWidget.renderWidgetString(HtmlWidget.java:130) at org.ofbiz.widget.screen.ModelScreenWidget$PlatformSpecific.renderWidgetString(ModelScreenWidget.java:920) at org.ofbiz.widget.screen.ModelScreenWidget.renderSubWidgetsString(ModelScreenWidget.java:104) at org.ofbiz.widget.screen.ModelScreenWidget$Section.renderWidgetString(ModelScreenWidget.java:191) at org.ofbiz.widget.screen.ModelScreen.renderScreenString(ModelScreen.java:396) ... 60 more